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New cancer cells exist an ever-changing ecology and are subject to evolutionary pressures just like any species in nature. This edited book explores the following themes: 1 how the dynamics of mutation, epigenetics, and gene expression noise are sources of genetic diversity; 2 how scarce resources influence cancer therapy resistance; 3 how predator-prey dynamics are mirrored in immune-cancer cross-talk; 4 how cancer cells parallel niche construction theory; 5 how changing fitness landscapes enable cancer growth; and 6 how cancer cells interact within the body. The book is a resource for understanding cancer as a disease of multicellularity grounded in evolutionary principles. By using this knowledge, researchers are starting to exploit these behaviors for treatment paradigms--
| Author: Jason A Somarelli, Norman A Johnson |
| Publisher: CRC Press |
| Publication Date: May 29, 2024 |
| Number of Pages: NA pages |
| Language: English |
| Binding: Hardcover |
| ISBN-10: 1032310782 |
| ISBN-13: 9781032310787 |
