M??ler Cells in the Healthy and Diseased Retina

M?ller cells may be used in the future for novel therapeutic strategies to protect neurons against apoptosis (for example, somatic gene therapy), or to differentiate retinal neurons from M?ller/stem cells. Meanwhile, a proper understanding of the gliotic responses of M?ller cells in the diseased retina, and of their protective vs. detrimental effects, is essential for the development of efficient therapeutic strategies that use and stimulate the neuron-supportive/-protective - and prevent the destructive - mechanisms of gliosis.