In this revised and expanded second edition, seasoned experts describe in step-by-step detail their best state-of-the-art techniques for studying neuronal cell death. These readily reproducible methods solve a wide variety of research problems, including the detection of the key proteins involved in neuronal apoptosis (Bax protein, cytochrome c, and caspases), the direct assessment of the role of pro-apoptotic proteins in neurons by viral infections and microinjections, and the detection of pro-apoptotic proteins in situ. There are also hands-on methods for the study of apoptosis mechanisms in neuronal compartments, for studying synaptosis, and for establishing gene expression profiles in neurodegenerative brain tissues by using DNA microarrays.
| Author: Andr?a C. LeBlanc |
| Publisher: Humana |
| Publication Date: Feb 12, 2002 |
| Number of Pages: 250 pages |
| Binding: Hardback or Cased Book |
| ISBN-10: 1588290123 |
| ISBN-13: 9781588290120 |
