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Humana

Drug Metabolism and Transport: Molecular Methods and Mechanisms

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Product Code: 9781588293244
ISBN13: 9781588293244
Condition: New
$180.44

Drug Metabolism and Transport: Molecular Methods and Mechanisms

$180.44
 
A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy.


Author: Lawrence H. Lash
Publisher: Humana
Publication Date: Sep 24, 2004
Number of Pages: 388 pages
Binding: Hardback or Cased Book
ISBN-10: 1588293246
ISBN-13: 9781588293244
 

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