A panel of internationally recognized research scientists and clinical investigators brings together a diverse collection of readily reproducible methods for identifying and quantifying a large number of specific genetic abnormalities associated with the broad spectrum of myeloid malignancies. Highlights include techniques for the detection of BCR-ABL mutations and resistance to imatinib mesylate, detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia, classification of AML by DNA-oligonucleotide microarrays, and detection of the V617F JAK2 mutation in myeloproliferative disorders. In addition to gene rearrangments, other prognostically relevant molecular lesions such as FLT3 mutations and WT-1 overexpression are covered.
| Author: Harry Iland |
| Publisher: Humana |
| Publication Date: Nov 15, 2005 |
| Number of Pages: 307 pages |
| Binding: Hardback or Cased Book |
| ISBN-10: 1588294854 |
| ISBN-13: 9781588294852 |
Related Products
Independently Published
Acupressure and Food Therapy for Acute Myeloid Leukemia (AML): Acute Myeloid Leukemia (AML)
$30.45
