Springer
Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of α-Aryl Ketones
Product Code:
9783319205434
ISBN13:
9783319205434
Condition:
New
$118.37
Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of α-Aryl Ketones
$118.37
This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis. Firstly, a new methodology, developed by our research group, which allows the asymmetric synthesis of lactones, a structural unit ubiquitous in natural products, was utilised in the synthesis of a number of natural product analogues that showed significant biological activity. Secondly, the development of a catalytic asymmetric synthesis of a key structural motif present in a number of natural products and pharmaceuticals was accomplished. During the course of this work we discovered dual stereo control, which is significant because it allows the configuration of a new stereo centre to be controlled by a simple change of proton source.
| Author: Robert Doran |
| Publisher: Springer |
| Publication Date: Jul 09, 2015 |
| Number of Pages: 202 pages |
| Binding: Hardback or Cased Book |
| ISBN-10: 3319205439 |
| ISBN-13: 9783319205434 |
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