Springer
Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
Product Code:
9783319422213
ISBN13:
9783319422213
Condition:
New
$118.37
Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
$118.37
This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
| Author: Emmanuel Donnadieu |
| Publisher: Springer |
| Publication Date: Sep 06, 2016 |
| Number of Pages: 199 pages |
| Binding: Hardback or Cased Book |
| ISBN-10: 3319422219 |
| ISBN-13: 9783319422213 |
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