Tissue Repair and Fibrosis: The Role of the Myofibroblast

Some Historical and Philosophical Reflections on the Myofibroblast Concept.- Transcriptional Regulation of the Desmin and SM22 Genes in Vascular Smooth Muscle Cells.- Modulation of Myofibroblast and Smooth-Muscle Phenotypes in the Lung.- Role of Platelet-Derived Growth Factors in Angiogenesis and Alveogenesis.- Transforming Growth Factor-? Gene Transfer to the Lung Induces Myofibroblast Presence and Pulmonary Fibrosis.- Transforming Growth Factor-? Induction of ?-Smooth Muscle Actin is Dependent on the Deformability of the Collagen Matrix.- Signal Transduction Pathways Activated During Fibroblast Contraction of Collagen Matrices.- Extracellular Matrix, Integrins and Focal Adhesions.- What Is New in Mechanical Properties of Tissue-Engineered Organs.- Fibroblast - Cytokine - Extracellular Matrix Interactions in Wound Repair.- Myofibroblastic Differentiation and Extracellular Matrix Deposition in Early Stages of Cholestatic Fibrosis in Rat Liver.- Gene Therapy of Wounds with Growth Factors.- What's New in Human Wound-Healing Myofibroblasts?.- The Myofibroblast in Neoplasia.- The Concept of Organizing Pneumonia.- Endothelial Repair in Atherogenesis.- Glomerulosclerosis: The Role of Interstitial Myofibroblasts in its Progression.- The Myofibroblast as an Inflammatory Cell in Pulmonary Fibrosis.- Cell-Cell and Cell-Matrix Interactions During Breast Cancer Progression.- Hepatocyte Growth Factor Secreted by Human Liver Myofibroblasts Increases Invasiveness of Hepatocellular Carcinoma Cells.- Interplay of Matrix and Myofibroblasts During Hepatic Fibrogenesis.

Author: Alexis Desmouliere

Publisher: Springer

Publication Date: Apr 14, 1999

Number of Pages: 248 pages

Binding: Hardback or Cased Book

ISBN-10: 3540652442

ISBN-13: 9783540652441