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Springer

Clostridium Difficile

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Product Code: 9783540672913
ISBN13: 9783540672913
Condition: New
$180.44

Clostridium Difficile

$180.44
 
Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to pseudomembranous colitis. This volume gives new insights into the microbiology, diagnostics and epidemiology of Clostridium difficile and describes recent strategies in treatment of diseases caused by this agent. Main parts of the volume are devoted to Clostridium difficile toxins A and B which are the major virulence factors. The molecular biology, biochemistry, pharmacology and cell biology of these toxins which are the prototypes of a new family of large clostridial cytotoxins is described in great detail. Clostridium difficile toxins act as glucosyltransferases to inactivate small GTP-binding proteins of the Rho family which are involved in regulation of the actin cytoskeleton, cell adhesion and various signaling processes.


Author: K. Aktories
Publisher: Springer
Publication Date: Jul 06, 2000
Number of Pages: 150 pages
Binding: Hardback or Cased Book
ISBN-10: 3540672915
ISBN-13: 9783540672913
 

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