A first edition of this book appeared in Russian language in 1983. Since those days the interest in proteolytic enzymes has acquired a new impulse due to advances in genetic engineering techniques, which facilitated structural and func- tional studies of the enzymes. Much more data on a crucial role of proteases in biological processes in norm and pathology are available now. Information that appeared in the past 8 years prompted a renewal of the book and furnishing a supplement especially made for the English edition. The book retains the presentation of the previous edition and yet enlarges the scope to cover the methods for site-directed mutagenesis of amide hydrolases, catalyti- cally active antibodies, etc. I have tried to preserve the book as a means of reference for the reader. A list of enzymes has been expanded and the biblio- graphy up to 1990 enlarged by half as much. I am grateful to the translators T. E. Chernichko, N. 1. Loboda and my co- worker Dr. S. L. Alexandrov for their assistance in the preparation ofthis edition and I feel happy that my book is now available for enzymologists abroad.
| Author: Vladimir K. Antonov |
| Publisher: Springer |
| Publication Date: Nov 21, 2012 |
| Number of Pages: 495 pages |
| Binding: Paperback or Softback |
| ISBN-10: 3662009811 |
| ISBN-13: 9783662009819 |
