This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.
| Author: G. Jeanette Thorbecke |
| Publisher: Springer |
| Publication Date: Jan 22, 2013 |
| Number of Pages: 241 pages |
| Binding: Paperback or Softback |
| ISBN-10: 3662131439 |
| ISBN-13: 9783662131435 |
