Metronomic Chemotherapy: Pharmacology and Clinical Applications

This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.

Author: Guido Bocci

Publisher: Springer

Publication Date: Sep 26, 2014

Number of Pages: 295 pages

Binding: Hardback or Cased Book

ISBN-10: 3662436035

ISBN-13: 9783662436035