A simple, sensitive, rapid and selective isocratic reversed phase High Performance Liquid Chromatographic (HPLC) method has been developed for Zopiclone from bulk drug using a mobile phase consisting mixture of Acetonitrile: Buffer (pH 2.8) (80:20v/v) Composition of buffer: (0.272gm in 200ml HPLC water and pH adjusted to 2.8 using ortho Phosphoric acid) at the flow rate of 1.0 mL/min. A Cosmosil C18 (250 cm x 4.6 mm, 5 μm) column was used as stationary phase.
| Author: Rahul Khaire |
| Publisher: LAP Lambert Academic Publishing |
| Publication Date: May 27, 2020 |
| Number of Pages: 120 pages |
| Binding: Paperback or Softback |
| ISBN-10: 6202563710 |
| ISBN-13: 9786202563710 |