Scholars' Press
Overview of Malaria Infection and Haematological Indices in Africa
Product Code:
9786206772170
ISBN13:
9786206772170
Condition:
New
$54.24
Overview of Malaria Infection and Haematological Indices in Africa
$54.24
Malaria, a severe parasitic disease transmitted by Anopheles mosquitoes, is caused by various Plasmodium species, with P. falciparum and P. vivax posing the greatest threat. While most infections are uncomplicated, a small percentage progresses to severe malaria, characterized by disruptions in immune cell profiles and increased cytokine levels. Severe P. falciparum malaria is associated with elevated plasma cytokines, T cell lymphopenia, and impaired T cell function. Treatment aims to restore immune cell balance, particularly CD3+, CD4+, and CD8+ cells. Protective immunity involves CD8+ T cells and cytokines like IFN-γ and TNF, while CD4+ T cells combat erythrocytic parasites through cytokine secretion and macrophage activation. Regulatory T cells also play a role, highlighting the importance of cytokine balance in malaria. Additionally, factors like antigen affinity influence T helper lymphocyte differentiation, affecting immune responses to the disease.
| Author: Samuel Antwi-Baffour |
| Publisher: Scholars' Press |
| Publication Date: Oct 22, 2024 |
| Number of Pages: 84 pages |
| Binding: Paperback or Softback |
| ISBN-10: 6206772179 |
| ISBN-13: 9786206772170 |
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