Our Knowledge Publishing
Understanding the clinical evolution of Sickle Cell Anaemia
Product Code:
9786207532674
ISBN13:
9786207532674
Condition:
New
$66.00
$65.28
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Understanding the clinical evolution of Sickle Cell Anaemia
$66.00
$65.28
Sale 1%
Sickle cell anaemia is a disease that has direct implications for the vascular environment due to the polymerisation of haemoglobin S inside the erythrocyte, making them sickle and rigid. The two main phenomena that occur in FA, intravascular haemolysis and vaso-occlusion, generate disturbances in the vasculature of these patients and are responsible for a series of clinical complications. However, vaso-occlusion is a determining factor in clinical evolution, as the endothelium is responsible for vascular homeostasis, and any factor that could upset the balance, such as sickle cell erythrocytes occluding the vessels, triggers a cascade of pathophysiological events. In view of this, our aim was to investigate the influence of genetic polymorphisms that are directly or indirectly involved in vaso-occlusive processes on the clinical variability of sickle cell anaemia.
| Author: Aylla N?ia L. M. Da Silva Dos Santos |
| Publisher: Our Knowledge Publishing |
| Publication Date: May 12, 2024 |
| Number of Pages: 80 pages |
| Binding: Paperback or Softback |
| ISBN-10: 6207532678 |
| ISBN-13: 9786207532674 |
