Creatine and Creatine Kinase in Health and Disease

A number of beneficial health effects have been ascribed to oral creatine supplementation. Creatine may even improve memory and intelligence.

In this book, emphasis is placed on the intricate interplay between creatine and creatine kinase function on one hand and proper brain function, neurodegenerative disease and/or neuroprotection on the other. The book also elaborates on the recently identified inborn errors of creatine biosynthesis and transport, the so-called cerebral creatine deficiency syndromes and discusses the muscle growth- and strength-promoting effects, the pharmacokinetics and the safety of oral creatine supplementation.

The book outlines the emerging systems biology approaches for understanding the pleiotropic effects of creatine and creatine kinase, and hypothesizes on the most promising and influential future avenues of research.