Observations on the Changes of the Air and the Concomitant Epidemical Diseases in the Island of Barbadoes, 1752-1758

Observations on the Changes of the Air and the Concomitant Epidemical Diseases in the Island of Barbadoes was first published in 1759 in London. Remarkably, a third edition was published in Philadelphia in 1812, with praise and annotations by the famous American physician Dr Benjamin Rush, and with good reason.

It is certainly the first comprehensive documentation of an epidemiological nature, in English, in the Caribbean, and justifies the title "first Caribbean epidemiologist" for Dr Hillary. He made rigorous observations and clear deductions that have stood the test of time surprisingly well. As Sir George Alleyne, director emeritus of PAHO, says: "We marvel at the conclusions he drew from his observations without the use of the technology which we have at our disposal. We are surprised by the accuracy of the symptomatology he describes."

Indeed, Hillary is famous for the earliest description of tropical sprue, but his description of what seemed to be yellow fever but "was not contagious", as yellow fever was then thought to be, was absolutely accurate and this "Barbados jaundice" turned out to be leptospirosis. His methods, his clinical skills and his eloquent writing deserve to be widely read.