Biomarkers used in Alzheimer's disease

Dive into the essential world of Alzheimer's disease biomarkers with this comprehensive guide. "Biomarkers in Alzheimer's Disease" explores the latest advancements and methodologies for early detection, diagnostic accuracy, and disease progression tracking. With Alzheimer's being a leading cause of dementia worldwide, early identification is critical-and biomarkers provide a promising avenue for this. This book details key categories, including imaging biomarkers, cerebrospinal fluid (CSF) markers, blood-based markers, and genetic indicators such as the APOE ε4 allele.

Inside, you'll discover how imaging techniques like MRI and PET scans reveal amyloid and tau protein buildup in the brain, while CSF markers such as amyloid-beta and tau proteins show molecular-level changes. Emerging blood-based biomarkers offer non-invasive options, making them invaluable for broad-scale screening. This text also explores ethical considerations, challenges in standardization, and the potential of multi-modal approaches combining biomarkers with machine learning for advanced, personalized care. Whether you are a medical professional, researcher, or student, this book provides essential insights into transforming Alzheimer's diagnosis and management.

Key Features:

• In-depth analysis of biomarker categories: amyloid, tau, neurodegeneration, and neuroinflammation markers.
• Detailed examination of genetic risk factors and the role of the APOE ε4 allele.
• Insights into novel biomarkers and emerging blood-based, non-invasive options.
• Ethical, psychosocial, and accessibility discussions around Alzheimer's diagnosis.
• The role of biomarkers in clinical trials and therapeutic decision-making.

Equip yourself with cutting-edge knowledge to better understand Alzheimer's disease progression and contribute to future innovations in diagnostics and treatment.